Of the fatal crashes, at least five involved driver impairment.
The number of traffic fatalities is down from the holiday last year, when 25 people died in 24 crashes, according to the OSHP.
Troopers this year made 536 arrests for impaired driving and 368 for drug-related charges.
The highway patrol responded to 534 crashes and made more than 40,000 traffic contacts, which included providing assistance to more than 2,700 motorists.
To report impaired drivers or drug activity, motorists can call #677.
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