Pickard was stellar in Edmonton's 5-4 overtime win in Game 2 with 28 saves, but he appeared uncomfortable in the third period and was seen shaking out his left leg.
Pickard replaced regular-season starter Skinner when the Oilers trailed the Kings 2-0 in the first round.
The Oilers won six in a row with Pickard in net and took a 2-0 series lead home from Las Vegas to Rogers Place.
Skinner is 19-17 in career playoff games with the Oilers.
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