As he claimed victory early Wednesday, Trump urged Americans to "come together as one united people."
"This is not the outcome we wanted or that we worked so hard for," Clinton said on Wednesday. "And I am sorry, that we did not win this election for the values we share and the vision for our country. … I know how disappointed you feel, because I feel it too, and so do tens of millions of Americans who invested their hopes and dreams in this effort. This is painful, and it will be for a long time."
Clinton became the Democratic nominee for president after a contentious race against U.S. Sen. Bernie Sanders, from Vermond.
"This loss hurts, but please, never stop believing that fighting for what's right is worth it," Clinton said. "I know we have still not shattered that highest, hardest glass ceiling but someday, someone will, and hopefully sooner than we might think."
Clinton's running mate, U.S. Sen. Tim Kaine, from Virginia, also thanked supporters Wednesday and lauded Clinton as a "history maker."
>> PHOTOS: Election Night 2016
"She has been, and is, a great history maker," Kaine said. "She has made history in a nation that has done so many things, but (it) has been uniquely difficult for a woman to win elected office. She became the first woman nominee, and last night, she won the popular vote of America."
According to numbers released by The Associated Press, Clinton had secured 188,810 more individual votes than Trump by 12:10 p.m. She failed, however, to get the 270 electoral votes needed to win the election.