Geisel's first book "And to Think That I Saw it on Mulberry Street," was rejected by 27 publishers before it was printed by Vanguard Press. He eventually wrote and illustrated 44 children's books.
Over the course of his career, Geisel spent 15 years creating advertising campaigns for Standard Oil.
He was editor of The Jack-O-Lantern, a humor magazine at Dartmouth College. When he was thrown off staff after getting caught throwing a party that served alcohol (during Prohibition) he developed the nom de plume "Seuss" and continued contributing to the magazine.
In addition to cartooning in various mediums, Geisel was an accomplished sculptor.
Geisel's definitive work, "The Cat in the Hat," was created with the directive from publisher Houghton Mifflin to use 225 "new reader" vocabulary words.
Among his accolades, Geisel was honored with a Pulitzer Prize, two Oscars, two Emmys and a Peabody award.