The drawing is set for 11 p.m. EST but it usually takes a couple hours before it's clear if there is a winner.
The $1.1 billion prize is for a winner who chooses to be paid through an annuity with 30 payments over 29 years. Winners usually prefer cash, which for Tuesday night's drawing would be an estimated $568.7 million.
Mega Millions is played in 45 states as well as Washington, D.C., and the U.S. Virgin Islands.