20-year-old Taylor Burns, of Saint Henry, suffered a medical condition while driving north and traveled off the right side of the road. Her vehicle went through a fence before striking a tree head-on.
Darke County Deputies, Greenville Township Fire and Rescue and Ansonia Fire and Rescue were called to the scene around 1:07 p.m.
Burns and the front-seat passenger, 20-year-old Kendra Rose, of Burkettsville, were both transported to Wayne HealthCare for injuries. Rose was then transported to Miami Valley Hospital for a leg injury.
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