Troopers responded to reports of a crash around 7:30 p.m. on state Route 72 near Hedgely Road, the patrol said.
Nelson was driving a Ford F-150 south on state Route 72 when it went off the left side of the roadway and struck a rock retaining wall and then a utility pole.
Debris from the crash caused minor damage to a second vehicle, the patrol said.
Nelson was taken to Mercy Health - Springfield Regional Medical Center and later transferred to Miami Valley Hospital in Dayton, where Nelson succumbed to his injuries.
State Route 72 was closed in both directions for about three hours and remained restricted to one lane throughout the night while Ohio Edison made repairs to the utility lines.
The crash remains under investigation.
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