The victim, a male believed to be in his 50s, was taken first to Springfield Regional Medical Center and then to Miami Valley Hospital, the chief said. He was home alone at the time.
The fire is believed to have started in a second-floor bedroom, Chief Clark said, and the cause remains under investigation.
Neighbors reported the fire, which spread to the attic and the roof.
Chief Clark said as much as 80% of the structure and contents have been damaged.
The Red Cross was called to assist the victim's family members, who arrived on scene as the flames were consuming their residence.
INITIAL REPORT
Crews are on the scene of a house fire reported in the 100 block of West Jamestown Street in South Charleston.
Crews were dispatched about 8:30 p.m. on reports of flames and smoke coming from the second floor of the two-story home.
There have been no reports of injury.
We have a crew on the way. We will update this developing report as we learn more.
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