The truck's owner told police he noticed the vehicle was missing from the Salvation Army parking lot he leases space from in the 8000 block of South Wind Drive.
Originally scheduled for a trip to Pennsylvania, the truck is carrying a shipment of beer from Miller Brewing Company, according to dispatchers.
Initial reports indicate the semi-trailer is red in color with black lettering on its side.
Anyone with information on the truck's location is encouraged to call the Montgomery County Sheriff's Office at 937-225-4357.
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