The No. 4-seeded Fritz's exit means the U.S. drought will continue without a male singles champion at any major since 2003, when Andy Roddick won in New York.
On Friday, Djokovic will play in his fourth Slam semifinal of the season and take on five-time major champion Carlos Alcaraz, who hasn't dropped a set in the tournament. He was a 6-4, 6-2, 6-4 winner against No. 20 Jiri Lehecka earlier Tuesday.
Djokovic leads No. 2 seed Alcaraz 5-3 head-to-head, winning their two most recent matchups — in the Australian Open quarterfinals this January and in the final at the Paris Olympics last year, when the Serbian finally fulfilled his wish to win a gold medal for his country.
The last two men’s quarterfinals are Wednesday: Alex de Minaur vs. Felix Auger-Aliassime, and defending champion Jannik Sinner vs. Lorenzo Musetti in an all-Italian matchup at night.
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Howard Fendrich has been the AP’s tennis writer since 2002. Find his stories here: https://apnews.com/author/howard-fendrich. More AP tennis: https://apnews.com/hub/tennis