Sanders said no and dismissed Ryan's question as "absolutely ridiculous."
"That is not illogical, irrational. It is a real question on the table that a White House does not want to deal with," Ryan said on CNN.
Ryan and Sanders have had contentious exchanges before during press briefings, and Ryan even sparked a Twitter feud with Sanders over whether the press secretary actually baked a pie she posted a picture of.
Ryan has also said before that she's gotten death threats. After asking former press secretary Sean Spicer about the perception of connections between the administration and Russia, Spicer told Ryan to "please stop shaking your head" during his answer.
"Unfortunately, I was roadkill today," Ryan said after the briefing. Ryan went to the FBI with death threats she had received after that exchange, too, the Washington Post reported.