Dayton (15-7, 7-2) moved into third place all by itself in the Atlantic 10 Conference as Duquesne fell to 15-7 and 6-3.
Obi Toppin led the Flyers with a career-high 26 points. He made 11 of 16 shots from the field. Crutcher scored 16. Eric Williams Jr. scored 20 for the Dukes.
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Duquesne outscored the Flyers 15-0 from 3-point range and took a 36-28 halftime lead.
The Dukes made 5 of 12 3-pointers. The Flyers missed all eight of their 3-point attempts.
Duquesne took control with a 12-2 run after the game was tied at 15-15. The Dukes led by as many as 14 points, 32-18. Dayton ended the half on a 10-4 run.
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Obi Toppin led Dayton with 12 points on 5-of-7 shooting. He had two dunks. Jalen Crutcher, Ryan Mikesell and Trey Landers each had four points.
Sincere Carry led Duquesne with 11 points. Duquense scored 13 points off seven Dayton turnovers. The Dukes committed three turnovers.