Obi Toppin led Dayton with 19 points. Jalen Crutcher scored 13.
AJ Wilson scored 18 for George Mason (15-13, 4-11), which is tied for 11th place with La Salle.
Here’s what the victory means for Dayton:
• Dayton set a school record for regular-season victories, passing the 2008-09 team that finished the regular season 25-6.
• Dayton has won 17 games in a row. It’s the second longest winning streak in one season in school history. The 1951-52 team won 20 straight games.
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• Dayton’s winning streak is the eighth longest in Atlantic 10 Conference history and the longest since Saint Louis won 19 straight in the 2013-14 season.
• Dayton moved within two victories of tying the school record for wins in a season. The 1951-52 team finished 28-5.
• Dayton became the fourth team in the nation to reach 26 victories this season, joining Gonzaga (27-2), San Diego State (26-1) and Liberty (26-3).
The Flyers made 11 of 16 shots from 2-point range but 2 of 12 from 3-point range on their way to a 30-25 halftime lead.
It was the 27th time in 29 games Dayton has led or been tied at halftime. It trailed at Saint Louis and at home against Duquesne in its last game.
Dayton did not trail in the first half and led by as many as eight points.
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Crutcher led Dayton with nine points. Rodney Chatman had seven. Obi Toppin scored six. Ryan Mikesell and Trey Landers each scored four.
AJ Wilson scored eight points for the Patriots.
Dayton shot 46.4 percent from the field. George Mason shot 40 percent.
The No. 4 Flyers became the highest-ranked team to play at EagleBank Arena, which opened in 1985. No. 6 Georgetown beat George Mason 75-63 in the arena’s inaugural season.
George Mason entered the game with a 1-3 record against top-five teams. Its lone win came against No. 2 Connecticut in the Elite Eight in 2006.