He still has 552 yards on 96 carries, trailing Williams’ 783 yards on 117 carries.
Henderson did not play the last two games, leaving Williams to carried 41 times for 258 yards. He was last seen in uniform running for a back-breaking touchdown at Penn State three weeks ago.
Williams left the game last week in the second quarter after appearing to roll over his right ankle on a tackle. He needed assistance getting off the field, but Day said he did not expect the injury to be long-term.
That left Hayden and Xavier Johnson, who is typically a receiver, to man the backfield for the last 2 1/2 quarters against the Hoosiers.
The only starter out is Jaxon Smith-Njigba, who was hurt in the opener against Notre Dame and was last seen on the field Oct. 22 against Iowa when he appeared to aggravate his hamstring injury.
Right tackle Dawand Jones also is back in the lineup after missing last week’s win over Indiana with an unidentified injury.