The new guidance represents another carefully calibrated step on the road back to normal from the coronavirus outbreak that has killed over 570,000 people in U.S.
For most of the past year, the CDC had been advising Americans to wear masks outdoors if they are within 6 feet of each other.
The change comes as more than half of U.S. adults have gotten at least one dose of coronavirus vaccine, and more than a third have been fully vaccinated.
“It’s the return of freedom,” said Dr. Mike Saag, an infectious disease expert at the University of Alabama at Birmingham who welcomed the change. “It’s the return of us being able to do normal activities again. We’re not there yet, but we’re on the exit ramp. And that’s a beautiful thing.”
More people need to be vaccinated, and concerns persist about variants and other possible shifts in the epidemic. But Saag said the new guidance is a sensible reward following the development and distribution of effective vaccines and about 140 million Americans stepping forward to get their shots.
The CDC, which has been cautious in its guidance during the crisis, essentially endorsed what many Americans have already been doing over the past several weeks.
The CDC says that fully vaccinated or not, people do not have to wear masks outdoors when they walk, bike or run alone or with members of their household. They can also go maskless in small outdoor gatherings with fully vaccinated people.
But from there, the CDC has differing guidance for people who are fully vaccinated and those who are not.
Unvaccinated people — defined by the CDC as those who have yet to receive both doses of the Pfizer or Moderna vaccine or the one-shot Johnson & Johnson formula — should wear masks at outdoor gatherings that include other unvaccinated people. They also should keep using masks at outdoor restaurants.
Fully vaccinated people do not need to cover up in those situations, the CDC says.
However, everyone should keep wearing masks at crowded outdoor events such as concerts or sporting events, the CDC says.
And the agency continues to recommend masks at indoor public places, such as hair salons, restaurants, shopping centers, museums and movie theaters.
Dr. Babak Javid, a physician-scientist at the University of California, San Francisco, said the new CDC guidance is sensible.
“In the vast majority of outdoor scenarios, transmission risk is low,” Javid said.
Javid has favored outdoor mask-wearing requirements because he believes they increase indoor mask-wearing, but he said Americans can understand the relative risks and make good decisions.
“The key thing is to make sure people wear masks indoors” while in public spaces, he said.
He added: “I'm looking forward to mask-free existence.”
“The timing is right because we now have a fair amount of data about the scenarios where transmission occurs,” said Mercedes Carnethon, a professor and vice chair of preventive medicine at Northwestern University’s Feinberg School of Medicine in Chicago.
What’s more, she said, “the additional freedoms may serve as a motivator” for people to get vaccinated.
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AP medical writer Carla K. Johnson in Washington state contributed to this report.
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The Associated Press Health & Science Department receives support from the Howard Hughes Medical Institute’s Department of Science Education. The AP is solely responsible for all content.