The driver was thrown from the van and died at the scene, the OSHP said. Their identity is being withheld while law enforcement contacts their next of kin.
Following the crash, both lanes of I-70 East were closed, and I-70 West temporarily was down to one lane. The highway was closed for about five hours and has since reopened, OSHP said.
This crash remains under investigation.
Highway troopers were joined at the crash scene by the Clay Township Police Department, Brookville Police Department, Brookville Fire Department, Phillipsburg Fire Department, Englewood Truck Towing & Recovery, the Montgomery County Coroner’s Office and the Ohio Department of Transportation.