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Family members told police that both were believed to be traveling together to Columbus, and possibly on to Dayton.
Mansfield police are working with Dayton and Ashland police departments to help find the couple.
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Hayton stands 4 feet, 11 inches and weighs 100 pounds with hazel eyes and brown hair.
Burkhart stands 5 feet, 10 inches, weighs 175 pounds and has green eyes and blond hair.
Anyone with information on their whereabouts is urged to call local law enforcement or Mansfield police at 419-755-9724.