The plane will fly in the early morning hours, just above the tree tops, to administer Foray (Btk), a "naturally occurring bacterium found in the soil that interferes with the caterpillars' feeding cycles," according to the state.
The treatments are not toxic to humans, pets, birds or fish, according to the Department of Agriculture.
Gypsy moths are invasive insects, the state said, that can damage or destroy a tree in just two years of feeding on its leaves.
The Clark County area is one of 51 counties in the state with an established gypsy moth population.
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