Brown eclipsed the previous ACC freshman record of 42 points, set last season by Duke's Cooper Flagg. The 45 points also tied Hall of Famer Wes Unseld's single-game Louisville scoring mark, set on Dec. 1, 1967, against Georgetown College.
After up-and-down scoring outputs in five games since returning from a lower back injury, the heralded freshman guard had 21 points with five 3s by halftime before erasing LaBradford Smith's school freshman mark of 32 midway through the second.
Brown's record-tying 3 came with 2:09 remaining, bringing a huge cheer from a white-clad crowd of 14,389 eager to see if he'd approach Unseld's school mark.
He finished 14 of 23 from the field with a career-best 10 of 16 from beyond the arc, topping his previous best of 29 points against rival Kentucky in November. That had ranked fourth-best all time among Louisville freshmen coming in.
Louisville started off hot and didn't cool off much, shooting 58% in the first half and finishing 39 of 65 overall. The Cardinals' total included 18 3-pointers on 30 attempts, tying their second-highest output this season.
Ven-Allen Lubin had 20 points and Tre Holloman 19 for N.C. State (18-7, 9-3), which had won six in a row and entered 6-0 in ACC road games. The Wolfpack shot 41% and made just 18% from deep.
Conwell hit 10 of 14 shots and 5 of 6 from behind the arc.
Up next
N.C. State: Hosts Miami on Saturday.
Louisville: Takes on Baylor on Saturday in Fort Worth, Texas.
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