Wampler then scored again at the basket, and Smith cashed in on a left-handed scoop to give the Raiders had a 53-41 edge with 14:08 to go.
The Grizzlies went 0-for-7 from the field with four turnovers during the spree. They were out-scored, 23-2, over the first 7:45 of the second half, and the Raiders stretched their lead to 20 with 10 minutes to go.
Wright State, which plays its next four games at home, swept the season series from Oakland.
First-place Northern Kentucky (19-6, 9-3) beat visiting Detroit on Thursday to keep its one-game lead.