Cincinnati (2-3) has captured the Keg of Nails each of the last two seasons, including a 41-10 blowout a year ago. The victories are part of a 12-game conference winning streak.
Louisville is coming off a 56-0 rout of Memphis, its first shutout in four years. Quarterback Adam Froman says the Cardinals, picked to finish last in the league, believe they can compete for the Big East title.