Ohio State will be down at least one starter on offense, and another could miss the Buckeyes’ game against Indiana on Saturday.
Sophomore running back TreVeyon Henderson is out for a second straight game, and senior right tackle Dawand Jones is a game-time decision.
Cornerback Cam Brown is available after missing five of the past six games.
On the Hoosiers’ side, Alter graduate Connor Bazelak is expected to return as the starting quarterback after missing last week’s loss to Penn State.
With Henderson out again, Miyan Williams figures to get most of the carries. Head coach Ryan Day said Thursday he would like to play depth at the position this week, but Chip Trayanum is also a game-time decision.
If he is also sidelined, that would lead Dallan Hayden as the only other available scholarship back.
Injuries have been a major part of the story for Ohio State running backs in 2022.
Marcus Crowley medically retired in the offseason after suffering another major injury, and Evan Pryor went down with a knee injury in the preseason, leaving Ohio State with three healthy scholarship backs.
They also lost walk-on T.C. Caffey after he showed some promise in mop-up duty early in the season.
Henderson has missed all of two games and parts of others because of injury, and Williams also missed all of one game and part of another.
They have combined for 1,182 yards while Hayden has run for 255.
Trayanum began the season at linebacker, but he moved to running back — the position he played the previous two seasons at Arizona State — a few weeks ago with mounting depth problems there.
If Jones can’t so, fellow Indiana native Josh Fryar likely would start in his place at right tackle.
Jaxon Smith-Njigba also will not play as he continues to deal with a hamstring issue, and reserve center Toby Wilson is a game-time decision.