The Cincinnati Reds will play the Saint Louis Cardinals on Opening Day on April 1, 2021, at Great American Ball Park. The Reds play a three-game series against the Cardinals and then stay at home for three games against the Pittsburgh Pirates.
The Reds play interleague series against American League Central Division opponents. The 162-game schedule ends with a three-game series in Pittsburgh from Oct. 1-3.
The 2021 #Reds schedule is here! pic.twitter.com/8ZiQSVhmN7
— Cincinnati Reds (@Reds) July 9, 2020
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