While the traffic is reduced to one lane, it will be controlled by flaggers at each end directing traffic, officials said.
The temporary traffic control is anticipated to create a traffic backup along County Line and near the Dorothy Lane intersection.
The five-lane expansion work from Vale Drive to Dorothy is seen as a key to aid business growth at Miami Valley Research Park, a jobs hub that straddles Kettering and Beavercreek.
The widening, which began in June, is contracted to RB Jergens of Vandalia and scheduled to be completed in fall 2022, Kettering officials have said.
Federal funds will cover about 60% of the project, documents state. The remaining cost will be split 50/50 by Kettering and Beavercreek.
The two cities partnered to analyze traffic patterns for the project that will add a lane in each direction.
State officials have called MVRP key real estate for military-related contractors at Wright-Patterson Air Force Base.