The driver reportedly fell asleep.
The vehicle was hauling food from ice cream to steaks.
No one is hurt.
A possible detour around the area is U.S. 40 to Airport Access Rd to I-70.
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The right lane of Interstate 70 is closed again this afternoon for crews to clean up after a box truck went on its side during the morning commute.
The crash happened at the Stillwater River near the 30 mile marker around 5:15 a.m. The semi is off the highway.