No injuries were reported. The truck was hauling a trailer, which overturned on the ramp.
The I-70 west entrance ramp was closed as crews worked to clear the scene.
The National Weather Service cautioned drivers to watch out for slick roads Tuesday morning after the region saw its first widespread snowfall of the season.
The NWS reported as much as 4.5 inches of snow in Xenia as of 8:19 a.m. Tuesday, with most communities receiving around 2 inches.
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