Related: Divided Supreme Court weights LGBT people's rights
A key provision of the Civil Rights Act of 1964 known as Title 7 bars job discrimination because of sex, among other reasons. In recent years, some courts have read that language to include discrimination against LGBT people as a subset of sex discrimination.
“This might inspire us to take another run at something that might be bipartisan, but we’ll see what the court does. I wouldn’t be surprised if the court makes a decision that broadens the current interpretation of the civil rights laws. I just don’t know,” Portman said.
Related: Kasich to GOP: Get out of the 1980s
In March 2013, Portman reversed his opposition to gay marriage after his son, Will, then a junior at Yale University, came out to his parents as gay. Portman’s reversal drew fire from conservative political corners within his own party.
Portman said getting a non-discrimination law through the Senate could be more difficult because key Republican allies have left since ENDA passed the Senate in November 2013.
In June 2015 in a case originating in Ohio, the U.S. Supreme Court ruled 5-4 that the right for same-sex couples to marry is constitutionally guaranteed.
Related: Ohio lawmaker pushes LGBTQ anti-discrimination bill
At the state level, state Sen. Nickie Antonio, D-Lakewood, is sponsoring a bill that would prohibit discrimination against LGBTQ people in the workplace, housing and places of public accommodation. She has introduced the bill each legislative session since 2003.